Clinical Effect, Analysis of Amoxicillin Clavulanate Potassium Combined with Shenling Baizhu Powder in the Treatment of Gastric Ulcer with Helicobacter pylori Infection

نویسندگان

چکیده

We attempt to investigate the improvement of clinical efficacy amoxicillin-clavulanate potassium combined with Shenling Baizhu powder in treating gastric ulcer patients Helicobacter pylori infection and effect on related serum indexes. selected 90 complicated our hospital from January 2019 May 2021 randomly divided them into observation group (45 cases treated amoxicillin clavulanate powder) control potassium), compared both groups effective rate eradication (per-protocol analysis) before after treatment, mucosal cytokines (vascular endothelial growth factor, epidermal cyclooxygenase-2), matrix metalloproteinase indicators (procalcitonin, C-reactive protein, interleukin-6) concentration level changes. After possessed remarkably higher levels vascular factor cyclooxygenase-2 than (p<0.05); it lower procalcitonin, protein interleukin-6 metalloproteinase-7, metalloproteinase-9 plasma per-protocol analysis, radical cure (86.67 %) was (66.67 (p<0.05). Amoxicillin-clavulanate can significantly improve infection, increase clearance pylori, cellular reduce cytokines. The provide guidance value for effectively infection.

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ژورنال

عنوان ژورنال: Indian Journal of Pharmaceutical Sciences

سال: 2022

ISSN: ['0250-474X', '1998-3743']

DOI: https://doi.org/10.36468/pharmaceutical-sciences.spl.500